Thomas Wilson's essay on temperance is followed by his description of the effect of "spirituous liquors" on the human body. There are numerous references to America and the effects of rum upon the Indians "... rum, which destroys multitudes in America, and has even depopulated whole countries of Native Indians." He further describes a 1701 meeting on the topic as follows: "When the Sachems or chiefs of the Five NATIONS of the Mohawks were in England about twenty-five years ago... they earnestly in treated [sic] that no rum be sold to their people in the future because it made them mad, ungovernable and actually killed great number of them."
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